There has been an increasing interest in using medication for weight loss. Previously, only a few weight loss medications were approved by the FDA, such as phentermine (Lomaira and Adipex-P) and orlistat (Xenical and Alli). However, the introduction of Glucagon-like peptide-1 receptor agonists (GLP-1 receptor agonists) like Wegovy and Ozempic has gained significant media attention. These medications have seen a rise in online searches and prescriptions, as revealed by a study published in 2022.

With a wider range of weight loss medications now available, patients often wonder which one is the strongest or most effective. However, determining the right medication for an individual can be challenging, considering the diverse options and their pros and cons. It's essential to stay updated with the constantly evolving medical research. Therefore, it is very important to take these medications under the guided supervision by an experience medical professional.

Some commonly prescribed weight loss medications include Semaglutide (Wegovy, Ozempic). Initially introduced as Ozempic to lower blood sugar levels in patients with Type-2 diabetes, Semaglutide received FDA approval in 2021 for treating obesity, under the brand name Wegovy. Administered via subcutaneous injection, Semaglutide is approved for use in adults and children aged 12 years and older who have obesity (BMI ≥30 for adults, BMI ≥ 95th percentile for age and sex for children) or in adults with excess weight (BMI ≥27) accompanied by weight-related medical problems. The dosage gradually increases over 16 to 20 weeks, reaching 2.4 mg. Side effects can include gastrointestinal symptoms, headache, dizziness, and fatigue.

Recent results from the SELECT trial conducted by Novo Nordisk showed that a weekly dose of 2.4 mg of Semaglutide resulted in a 20% reduction in major adverse cardiovascular events among individuals with established cardiovascular disease and either overweight or obesity, without a prior history of diabetes. It's important to note that Semaglutide is contraindicated in patients with certain health factors that may place certain patients of risk of complications from the medication.